During the 1950s Morris published pioneering papers on infant mortality and did ground breaking research on the influence of physical exercise on coronary heart disease. His work in the late 1960s and early 1970s was concerned with cardiovascular disease. He wrote a pioneering textbook in 1957, Uses of Epidemiology, which was effectively a blueprint for […]

Full Figure and legend (14K) TopDiscussionThe aim of this study was to adapt an energy transfer assay to the detection of protein ubiquitination in living cells. Using arrestin as a model, we demonstrated that BRET can specifically detect both basal and dynamically regulated ubiquitination processes. Because it cannot be incorporated into proteins, the concentration of […]

The Rs 21,000 crore eyewear market in India, according to industry body ASSOCHAM, is projected to grow to Rs 43,000 crore by 2015, at a compounded annual growth rate of 30%. Eyewear brands are getting aggressive with sunglasses, prescription eyewear frames and lenses, contact lenses and intraocular lenses. While the share of organised eyewear is […]

In 1870 he began to assist Nottinghamshire, and in his first match for the county v. Kent, at the Crystal Palace played an innings of 60 and, in partnership with Daft, took the score to 100 after three wickets had fallen for 14. Owing to business claims he was seldom seen in first class cricket, […]

Within specific tissues, this local glucocorticoid availability is critically determined by intracellular glucocorticoid metabolism (23,24). This local ‘pre receptor’ regulation of glucocorticoid availability is mediated by the interconversion of hormonally active and inactive ligands by the two 11 hydroxysteroid dehydrogenase (11HSD) isoenzymes (23,24). The type 1 enzyme (11 HSD1) predominantly catalyses the formation of active […]

>>> A VERDICT TODAY IN THE MURDER TRIAL OF A HOMEOWNER IN SUBURBAN DETROIT WHO SHOT AND KILLED A YOUNG WOMAN HE CLAIMED WAS THREATENING AND BANGING ON HIS DOORS IN THE MIDDLE OF THE NIGHT. BUT THE JURY REJECTED HIS CLAIM THAT HE FEARED FOR HIS LIFE. NBC PETER ALEXANDER COVERING FOR US IN […]

‘I’m certainly much more conscious now of: “Are they OK?”, “Where are they?”‘ he said, as we grabbed a snack at the Union Club in Soho. In The Missing, his boy is played by Oliver Hunt. ‘I don’t have a son of my own, so it was thrilling to work with him. Allen Overy moved […]